Why AbbVie’s Global Alliance With Galapagos Is Good News for Investors

Since becoming an independent company late last year, AbbVie has been making significant progress. AbbVie shares have been among the best performers in the health care sector this year, gaining nearly 31% year-to-date. The gains have come Continue reading Why AbbVie’s Global Alliance With Galapagos Is Good News for Investors

New Compounds Display Strong Therapeutic Potential for Cystic Fibrosis

Sep. 30, 2013 — Cystic fibrosis is a lethal genetic disorder that in France affects one child per 4,500 births. An international team led by scientists at the Institut Fédératif de Recherche Necker-Enfants Malades (CNRS/Inserm/Université Paris Descartes)[1], led by Aleksander Edelman, has recently discovered two new compounds that could be used to treat patients carrying the most common mutation. Continue reading New Compounds Display Strong Therapeutic Potential for Cystic Fibrosis

If Chosen Wisely, Existing Drugs Fight Resistant Bugs

Science/AAAS | News
Fatal weakness. Pathogens such as methicillin-resistant Staphylococcus aureus (above) develop vulnerabilities as they evolve resistance to antibiotics. Choosing antibiotics that exploit these weaknesses can thwart resistant bacteria. Continue reading If Chosen Wisely, Existing Drugs Fight Resistant Bugs

Celtaxsys completes Phase I trial of cystic fibrosis drug

US-based clinical stage drug discovery and development firm Celtaxsys has completed Phase I clinical trial of its drug CTX-4430 to treat patients with cystic fibrosis (CF) lung disease.

Celtaxsys Aus, the company’s Australian subsidiary, has carried out the first of two clinical trials in Continue reading Celtaxsys completes Phase I trial of cystic fibrosis drug

Growing Lungs May Soon Be A Reality

Local researchers are working to advance stem cell research that will allow scientists to grow organs.

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Researchers from the Center for Regenerative Medicine, which is a collaboration of Boston Medical Center and Boston University scientists, are working to advance stem cell research in a way that will allow them to grow organs, including lungs, in the not-too-distant future. Continue reading Growing Lungs May Soon Be A Reality

Scientists pinpoint 105 additional genetic errors that cause cystic fibrosis

Of the over 1,900 errors already reported in the gene responsible for cystic fibrosis (CF), it is unclear how many of them actually contribute to the inherited disease. Now a team of researchers reports significant headway in figuring out which mutations are benign and which are deleterious. Continue reading Scientists pinpoint 105 additional genetic errors that cause cystic fibrosis

Vertex Updates Recent Progress and Upcoming Milestones in Clinical Development Programs

Vertex’s strategy in cystic fibrosis (CF) is to provide benefit to as many CF  patients as possible, and to maximize the benefit for these patients, with our  approved and investigational medicines. Continue reading Vertex Updates Recent Progress and Upcoming Milestones in Clinical Development Programs

Extended-Infusion Cefepime Reduces Mortality in Patients with Pseudomonas aeruginosa Infections; Bauer KA, West JE, O’Brien JM, Goff DA; Antimicrobial Agents & Chemotherapy (Apr 2013)

In an era of escalating resistance and lack of new antimicrobial discovery, stewardship programs must utilize knowledge of pharmacodynamics to achieve maximal exposure in the treatment of Pseudomonas aeruginosa infections. We evaluated the clinical and Continue reading Extended-Infusion Cefepime Reduces Mortality in Patients with Pseudomonas aeruginosa Infections; Bauer KA, West JE, O’Brien JM, Goff DA; Antimicrobial Agents & Chemotherapy (Apr 2013)

Novel Therapy Against Cystic Fibrosis Discovered by Researchers

A new study led by Dr Gergely Lukacs, from the  Physiology Department at McGill University, in Canada, reveals new information  about the disease known as cystic fibrosis. Cystic fibrosis (CF), also known as  mucoviscidosis, is a life threatening disease that severely affects the  digestive system and the lungs. Continue reading Novel Therapy Against Cystic Fibrosis Discovered by Researchers

Manchester Researchers Discover Half Of All Adults With Cystic Fibrosis Affected By Airborne Fungus

Experts believe a pioneering breakthrough by a Manchester hospital research team could pave the way for doctors to better understand and treat adults with Cystic Fibrosis (CF), helping them live longer and healthier lives. http://www.medicalnewstoday.com/releases/262897.php Continue reading Manchester Researchers Discover Half Of All Adults With Cystic Fibrosis Affected By Airborne Fungus