When two channels that are supposed to move chloride and sodium ions out of cells in the lungs fail to function properly, it leads to the mucus buildup seen in cystic fibrosis.
Japanese researchers have discovered that the channel dysfunctions also reduce the amount of zinc ions going into the lungs, further contributing to the thick mucus accumulation.
Their study, published in the journal EBioMedicine, is titled “Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells.” Continue reading Low Level of Zinc Ions in Lungs Contribute to Buildup of Mucus in CF
When people with cystic fibrosis head off to college the big decision is whether or not to live with a roommate. If we choose to live with roommates, for many of us it will be the first time we are very much sharing our cystic fibrosis with someone else. The need to perform Continue reading Making it Matter Ep. 30 – Living with a Roommate
I’m not naïve enough to think that I’m going to wake up tomorrow and find that my life is moving forward with cystic fibrosis in the rearview mirror.
We’re still a little bit away from that moment, but that doesn’t mean I don’t have high expectations for treatment development. Continue reading My Wish List for the New Year By Gunnar Esiason
A medical device for Cystic Fibrosis (CF) sufferers which lessens their exposure to infections resulting in fewer doctors’ visits, reduced antibiotic usage and shorter hospital stays, is expected to be market ready within two Continue reading New Cystic Fibrosis device to reduce antibiotic usage
Spitting is gross. It is rude, unhealthy and socially unacceptable (in public places at least).
Spitting is kind of like wetting the bed. People wet the bed when they are kids, college age and then when they are like 105, because I guess at that point no one Continue reading On Spitting and Cystic Fibrosis