Phase 1a study for drug to treat CF regardless of CF Mutation

http://www.businesswire.com/news/home/20171018005403/en/Synspira-Announces-Patient-Dosed-Phase-1a-Study

Synspira Announces First Patient Dosed in Phase 1a Study of SNSP113 in Cystic Fibrosis
— First-in-class drug candidate for treatment of cystic fibrosis regardless of genetic mutation — Continue reading Phase 1a study for drug to treat CF regardless of CF Mutation

Prometic’s PBI-4050 To Target Cystic Fibrosis As Its Next Orphan Indication

http://www.newswire.ca/news-releases/prometics-pbi-4050-to-target-cystic-fibrosis-as-its-next-orphan-indication-561768451.html

• Majority of cystic fibrosis (“CF”) patients develop diabetes and liver steatosis
• PBI-4050 shown to reduce fibrosis in the lungs, pancreas and liver in preclinical models
• PBI-4050 confirmed to reduce glycated hemoglobin in type 2 diabetes Continue reading Prometic’s PBI-4050 To Target Cystic Fibrosis As Its Next Orphan Indication

Pancreas Transplant for Cystic Fibrosis Patients with Exocrine Insufficiency

An analysis of organ transplant records between 1987 and 2014 suggests that cystic fibrosis patients who lose pancreatic function are failing to avail themselves of operations that could replace their damaged organs and restore their ability to digest food and manage blood sugar. Continue reading Pancreas Transplant for Cystic Fibrosis Patients with Exocrine Insufficiency

CU Hospital patient progressing after first lungs and liver transplant

A 30 -year old Nebraska man with cystic fibrosis who underwent the state’s first double-lung and liver transplant last week is breathing easily, up and walking around, his surgeon at the University of Colorado Hospital in Aurora said Monday. Continue reading CU Hospital patient progressing after first lungs and liver transplant

Pitt-led study suggests cystic fibrosis is 2 diseases, 1 doesn’t affect lungs

Cystic fibrosis (CF) could be considered two diseases, one that affects multiple organs including the lungs, and one that doesn’t affect the lungs at all, according to a multicenter team led by researchers at the University of Pittsburgh School of Medicine. The research, published online today in PLOS Continue reading Pitt-led study suggests cystic fibrosis is 2 diseases, 1 doesn’t affect lungs

Stem cell line could also advance research into liver cancers, cystic fibrosis

Published on March 1, 2013 at 12:00 AM
Chronic or acute, liver failure can be deadly. Toxins take over, the skin turns yellow and higher brain function slows.

“There is no effective therapy at the moment to deal with the toxins that build up in your body,” Continue reading Stem cell line could also advance research into liver cancers, cystic fibrosis